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- DirectorJames MangoldStarsWinona RyderAngelina JolieClea DuVallA directionless teenager, Susanna, is rushed to Claymoore, a mental institution, after a supposed suicide attempt. There, she befriends a group of troubled women who deeply influence her life.
- DirectorErik SkjoldbjærgStarsChristina RicciJonathan Rhys MeyersJessica LangeA young woman struggles with depression during her first year at Harvard.
- DirectorDavid O. RussellStarsBradley CooperJennifer LawrenceRobert De NiroAfter a stint in a mental institution, former teacher Pat Solitano moves back in with his parents and tries to reconcile with his ex-wife. Things get more challenging when Pat meets Tiffany, a mysterious girl with problems of her own.
- DirectorMichel GondryStarsJim CarreyKate WinsletTom WilkinsonWhen their relationship turns sour, a couple undergoes a medical procedure to have each other erased from their memories forever.
- DirectorCatherine HardwickeStarsEvan Rachel WoodHolly HunterNikki ReedA thirteen-year-old girl's relationship with her mother is put to the test as she discovers drugs, sex, and petty crime in the company of her cool but troubled best friend.
- DirectorShira PivenStarsKristen WiigJames MarsdenLinda CardelliniWhen Alice Klieg wins the Mega-Millions lottery, she immediately quits her psychiatric meds and buys her own talk show.
- DirectorMichael CristoferStarsAngelina JolieFaye DunawayElizabeth MitchellThe story of the life of Gia Carangi, a top fashion model from the late 1970s, from her meteoric rise to the forefront of the modeling industry, to her untimely death.
- DirectorTate TaylorStarsEmily BluntHaley BennettRebecca FergusonA divorcee becomes entangled in a missing persons investigation that promises to send shockwaves throughout her life.
- DirectorDavid FincherStarsBen AffleckRosamund PikeNeil Patrick HarrisWith his wife's disappearance having become the focus of an intense media circus, a man sees the spotlight turned on him when it's suspected that he may not be innocent.
- DirectorStephen DaldryStarsMeryl StreepNicole KidmanJulianne MooreThe story of how the novel "Mrs. Dalloway" affects three generations of women, all of whom, in one way or another, have had to deal with suicide in their lives.
- DirectorBob FosseStarsLiza MinnelliMichael YorkHelmut GriemA female girlie club entertainer in Weimar Republic era Berlin romances two men while the Nazi Party rises to power around them.
- DirectorPeter KosminskyStarsMichelle PfeifferRenée ZellwegerRobin WrightA teenager journeys through a series of foster homes after her mother goes to prison for committing a crime of passion.
- DirectorLyne CharleboisStarsIsabelle BlaisJean-Hugues AngladeAngèle CoutuAn erotic drama about a woman facing her 30th birthday who looks back at her life growing-up with her grandmother, crazy mother and her over-indulgence with men, sex and alcohol.
- DirectorTamra SattlerStarsDebbie CorsoPresh GrieshopTeresa LynneBorder _ is a compassionate documentary on the reality of a serious mental illness known as Borderline Personality Disorder. Four very different women are profiled, and their inspiring stories of recovery are shared.