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- CreatorKevin MurphyRockne S. O'BannonMichael TaylorStarsGrant BowlerStephanie LeonidasJulie BenzLife in the city of Defiance, in a near future after the arrival of different alien lifeforms to Earth.
- StarsRomano OrzariManuel TadrosJesse RathWhen the Duke of Milan is brutally murdered, the Assassin Giovanni Auditore is dispatched to investigate. The answers he uncovers implicate Italy's most powerful families reaching all the way back to the Vatican itself.
- CreatorDiablo CodyStarsToni ColletteJohn CorbettRosemarie DeWittA woman struggles to find a balance between her dissociative identity disorder and raising a dysfunctional family.
- DirectorKevin HooksBrad TurnerStarsWentworth MillerDominic PurcellWilliam FichtnerMichael and Sara wed, but the happiness is short-lived when the Feds apprehend her for the murder of Michael's mother, Christina. Once a hit is ordered on Sara, the team reunite to break out the increasingly vulnerable target.
- CreatorTom KapinosStarsDavid DuchovnyNatascha McElhoneEvan HandlerA writer tries to juggle his career, his relationship with his daughter and his ex-girlfriend, as well as his appetite for beautiful women.
- CreatorJohn LoganStarsJosh HartnettTimothy DaltonEva GreenExplorer Sir Malcolm Murray, American gunslinger Ethan Chandler, scientist Victor Frankenstein and medium Vanessa Ives unite to combat supernatural threats in Victorian London.
- CreatorBruno HellerStarsBen McKenzieJada Pinkett SmithDonal LogueThe story behind Detective James Gordon's rise to prominence in Gotham City in the years before Batman's arrival.
- CreatorGreg BerlantiGeoff JohnsAndrew KreisbergStarsGrant GustinCandice PattonDanielle PanabakerAfter being struck by lightning, Barry Allen wakes up from his coma to discover he's been given the power of super speed, becoming the Flash, and fighting crime in Central City.
- CreatorDarren StarStarsSarah Jessica ParkerKim CattrallKristin DavisFour female New Yorkers gossip about their sex lives (or lack thereof) and find new ways to deal with being a woman in the late 1990s.
- StarsPeter KrauseJulianna MarguliesPeter JacobsonA detective investigates a mysterious motel room which acts as a portal to anywhere in the world.
- CreatorCraig WrightStarsPeter KrauseDonald SutherlandWilliam BaldwinA lawyer is forced to take care of one of New York City's wealthiest families.
- StarsMcKenzie WestmoreGlenn HetrickVe NeillSpecial effects make up artists compete in challenges.
- StarsCaterina ScorsoneAndrew Lee PottsMatt FrewerEverything you know about Alice's Adventures in Wonderland is about to be turned upside down in this modern-day mini-series. The cast includes Kathy Bates, Caterina Scorsone, Matt Frewer, Harry Dean Stanton, and Tim Curry.
- CreatorMarc CherryStarsTeri HatcherFelicity HuffmanMarcia CrossSecrets and truths unfold through the lives of female friends in one suburban neighborhood after the mysterious suicide of a neighbor.
- CreatorBrad FalchukRyan MurphyHalley FeifferStarsLady GagaKathy BatesAngela BassettAn anthology series centering on different characters and locations, showcasing different aspects of horror.
- CreatorMatt PiedmontHarper SteeleStarsTobey MaguireKristen WiigWill FerrellCynthia and Devon are two siblings whose intense love drives everything and everyone around them to ruin.
- CreatorFrank DarabontStarsAndrew LincolnNorman ReedusMelissa McBrideSheriff Deputy Rick Grimes wakes up from a coma to learn the world is in ruins and must lead a group of survivors to stay alive.
- CreatorJason RothenbergStarsEliza TaylorBob MorleyMarie AvgeropoulosSet 97 years after a nuclear war destroyed civilization, when a spaceship housing humanity's lone survivors sends 100 juvenile delinquents back to Earth, hoping to repopulate the planet.
- CreatorDavid E. KelleyStarsRobin WilliamsSarah Michelle GellarJames WolkOut-of-the-box Simon Roberts runs an ad agency with his Type-A daughter Sydney.
- CreatorDavid S. GoyerStarsTom RileyGregg ChilingirianEros VlahosFollows Leonardo Da Vinci during his early days in Florence, as a young artist, inventor and dreamer, trying to change the future.
- CreatorRemi AubuchonRonald D. MooreStarsEric StoltzEsai MoralesPaula MalcomsonTwo families, the Graystones and the Adamas, live together on a peaceful planet known as Caprica, where a startling breakthrough in artificial intelligence brings about unforeseen consequences.
- CreatorAlfonso CuarónMark FriedmanStarsJake McLaughlinJohnny SequoyahJamie ChungA relationship forms between a gifted young girl and a man sprung from prison who has been tasked with protecting her from the evil elements that hunt her power.
- StarsAri GraynorSara GilbertRyan HansenCenters on a sexy, foul-mouthed divorcée who becomes a teacher to find her next husband.
- CreatorBill LawrenceStarsZach BraffDonald FaisonSarah ChalkeIn the unreal world of Sacred Heart Hospital, intern John "J.D." Dorian learns the ways of medicine, friendship and life.
- CreatorDavid X. CohenMatt GroeningStarsBilly WestJohn DiMaggioKatey SagalPhilip J. Fry, a pizza delivery boy, is accidentally frozen in 1999 and thawed out on New Year's Eve 2999.