Adult animation
I am not including anime on this list
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75 titles
- CreatorJames L. BrooksMatt GroeningSam SimonStarsDan CastellanetaNancy CartwrightHarry ShearerThe satiric half-hour adventures of a working-class family in the misfit city of Springfield.
- CreatorDan HarmonJustin RoilandStarsChris ParnellSpencer GrammerSarah ChalkeThe fractured domestic lives of a nihilistic mad scientist and his anxious grandson are further complicated by their inter-dimensional misadventures.
- CreatorRobert KirkmanRyan OttleyCory WalkerStarsSteven YeunJ.K. SimmonsSandra OhAn adult animated series based on the Skybound/Image comic about a teenager whose father is the most powerful superhero on the planet.
- CreatorJohn KricfalusiStarsJohn KricfalusiEric BauzaMike KricfalusiThe Chihuahua and Cat duo return for more adventures, but this time they are more adult-oriented.
- CreatorJesse HernandezRamon LopezStarsRamon LopezJesse HernandezRhia AbarquezTwo cousins (Phil and Jack) from completely different worlds (the Philippines and the SF Bay Area) are forced to live together by their overly controlling uncle, Tito Dick.It’s the nutshack
- CreatorSeth MacFarlaneDavid ZuckermanStarsAlex BorsteinSeth MacFarlaneSeth GreenIn a wacky Rhode Island town, a dysfunctional family strives to cope with everyday life as they are thrown from one crazy scenario to another.
- CreatorDavid X. CohenMatt GroeningStarsBilly WestJohn DiMaggioKatey SagalPhilip J. Fry, a pizza delivery boy, is accidentally frozen in 1999 and thawed out on New Year's Eve 2999.
- CreatorJ.J. VillardEric KaplanStarsTommy BlachaJ.J. VillardRobin Atkin DownesKing Star King is an intergalactic warrior who fights various evil foes throughout the Gigantiverse. Always by his side are his team of "strange heroes" which includes Hank Waffles, Pooza the Wizard, and Gurbles the flying robot bear.
- CreatorCharlie GrandyStarsMindy KalingGlenn HowertonSam RichardsonThe origin of the sleuth and member of the Mystery Inc. gang, Velma.
- StarsPatton OswaltAimee GarciaBen SchwartzIt centers around an egomaniacal supervillain with a really big head and a really little body, who struggles to maintain control of his evil organization and his demanding family.
- CreatorRaphael Bob-WaksbergStarsWill ArnettAmy SedarisAlison BrieBoJack Horseman was the star of the hit television show "Horsin' Around" in the '80s and '90s, but now he's washed up, living in Hollywood, complaining about everything, and wearing colorful sweaters.
- CreatorMatt MaiellaroDave WillisStarsDave WillisCarey MeansDana SnyderThe misadventures of a milkshake, an order of fries, a meatball, and their retired next door neighbor in the suburbs of New Jersey.
- CreatorTrey ParkerMatt StoneBrian GradenStarsTrey ParkerMatt StoneIsaac HayesFollows the misadventures of four irreverent grade-schoolers in the quiet, dysfunctional town of South Park, Colorado.
- CreatorWill CarsolaDave StewartStarsDave StewartKaitlyn RobrockWill CarsolaThe Goodman family lives with their lovable pet dog, Mr. Pickles, a deviant border collie with a secret satanic streak.
- CreatorAdam MutoPendleton WardStarsMadeleine MartinRoz RyanTom KennyFionna, her best friend Cake and the former Ice King, Simon Petrikov, embark on an adventure through the multiverse, dodging new threats and making self-discoveries along the way.
- CreatorJustin HalpernDean LoreyPatrick SchumackerStarsKaley CuocoLake BellAlan TudykThe series focuses on a single Harley Quinn, who sets off to make it on her own in Gotham City.
- CreatorGreg DanielsMike JudgeStarsMike JudgeKathy NajimyPamela AdlonA straight-laced propane salesman in Arlen, Texas tries to deal with the wacky antics of his family and friends, while also trying to keep his son in line.
- CreatorMike BarkerSeth MacFarlaneMatt WeitzmanStarsSeth MacFarlaneWendy SchaalScott GrimesThe escapades of Stan Smith, a conservative C.I.A. Agent dealing with family life, and keeping America safe.
- CreatorAdam ReedStarsH. Jon BenjaminJudy GreerAmber NashCovert black ops and espionage take a back seat to zany personalities and relationships between secret agents and drones.
- CreatorRichard AppelMike HenrySeth MacFarlaneStarsMike HenrySanaa LathanKevin Michael RichardsonCleveland Brown moves back to his hometown in Virginia, where he finds his high school sweetheart and her two troublemaking kids.
- CreatorJennifer FlackettAndrew GoldbergNick KrollStarsNick KrollJohn MulaneyJessi KleinTeenage friends find their lives upended by the wonders and horrors of puberty.
- CreatorPaulo LescautAnderson MahanskiFernando MendonçaStarsWillam BelliTrixie MattelD.J. 'Shangela' PierceThree gay co-workers at a department store lead double lives as superhero drag queens, fighting crime and other forces like an evil drag queen and a conservative politician.
- CreatorKevin KopelowStan LeeHeath SeifertStarsPamela AndersonTom KennyMaurice LaMarchePamela Anderson provides the voice of Erotica Jones who is stripper by night and superhero Stripperella by even later at night.
- CreatorMike McMahanJustin RoilandStarsThomas MiddleditchSean GiambroneMary MackA family of aliens move to middle America, where they debate whether life is better there or on their home planet.
- CreatorLoren BouchardJim DauteriveStarsH. Jon BenjaminDan MintzEugene MirmanBob Belcher runs a struggling burger shop with his wife and three children.