She is considered a pioneer of Czech rhythm and blues and rock and roll.
She began her career with an audition at the Semafor theater, from which Milos Forman made his directorial debut Konkurs. She was not accepted into the theater with the song Malagena, but the composer Karel Mares (then accompanist) noticed her.
In 1994, she returned to Prague permanently.
Currently, she is the presenter of the Czech radio station Country Radio with the author's program "Sklipek".
In February 1964, sixteen-year-old Yvonne Prenosilová recorded the Czech version of the song I'm Sorry from Brenda Lee. Even in the Czech version, the song became a hit and one of the best-selling Czech singles of the sixties.