London, April 6 (Ians) People exposed to higher levels of air pollution before the pandemic are likely to have lower antibody responses to Covid-19 vaccines, suggests a study.
In particular, exposure to fine particulate matter (PM2.5), nitrogen dioxide (NO2) and blank carbon (BC) was associated with about a 10 per cent decrease in IgM and IgG antibody responses in people without prior infection, said researchers from the Barcelona Institute for Global Health (ISGlobal), and the Germans Trias i Pujol Research Institute (Igtp) in Spain.
The fact that previous infections lead to higher vaccine responses could explain why the effect of pollutants was only observed in people without a prior infection.
However, the role of long-term exposure to air pollution on hybrid immunity (infection plus vaccination) deserves further investigation, the researchers warned, in the study published in Environmental Health Perspectives.
“Air pollution can induce chronic inflammation, which has been associated with a negative effect on vaccine efficacy,...
In particular, exposure to fine particulate matter (PM2.5), nitrogen dioxide (NO2) and blank carbon (BC) was associated with about a 10 per cent decrease in IgM and IgG antibody responses in people without prior infection, said researchers from the Barcelona Institute for Global Health (ISGlobal), and the Germans Trias i Pujol Research Institute (Igtp) in Spain.
The fact that previous infections lead to higher vaccine responses could explain why the effect of pollutants was only observed in people without a prior infection.
However, the role of long-term exposure to air pollution on hybrid immunity (infection plus vaccination) deserves further investigation, the researchers warned, in the study published in Environmental Health Perspectives.
“Air pollution can induce chronic inflammation, which has been associated with a negative effect on vaccine efficacy,...
- 4/6/2023
- by Agency News Desk
- GlamSham
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