- Midfielder for América de Cali (1996-2003), Boca Juniors (2003-2006, 2007-2009), S.C. Internacional (2006-07), UD Almería (2009-2011), A.E.K. Athens F.C. (2011-12), C.A. Independiente (2012-13), Barcelona S.C. (2013), Millonarios F.C. (2014-2015) and La Equidad (2016-2018), in all 582 games and 21 goals.
- Honours with América de Cali: Copa Merconorte (1999); Primera A (2000, 2001, 2002 Apertura). Honours with Boca Juniors: Argentine Primera División (Apertura 2003, Apertura 2005, Clausura 2006, Apertura 2008); Intercontinental Cup (2003); Copa Sudamericana (2004, 2005); Recopa Sudamericana (2005, 2008). Honours with S.C. Internacional: FIFA Club World Cup (2006); Recopa Sudamericana (2007).
- 41 appearances for Colombia National Football Team (1999-2009). Member of the Copa América 2001 and 2007 squads.
- Member of the Colombia National team who won the 2001 Copa América.
- Played well over 100 games for América de Cali.
- Father of Camila Vargas (b. 2006) and Luciana Vargas (b. 2012).
- Played well over 100 games for Boca Juniors.
- Co-owns, with Kilian Virviescas, a soccer school in Ibagué called "V&V Fútbol Club".
- In February 2017 he played his 600th game as professional.
- 2018: Retired from football at the age 38.
- Works as an analyst for ESPN Colombia.
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