This was the first of four feature films from RKO based on Harold Peary's popular radio character "The Great Gildersleeve" that aired on the NBC network from 1941 to 1950. The next two features would be released later the same year, and the fourth released the following year (1944).
Walter Tetley, who played the role of LeRoy on the radio, couldn't appear on screen because he was actually an adult playing a child character.
Although based on the radio program of the same name, Harold Peary(Gildy) and Lillian Randolph(Birdie) were the only radio performers to reprise their roles for the movie.