The film was a sequel to Warner Bros.' Janie (1944). Although a "Janie" series had been planned, Warner Bros. abandoned the idea after actress Joyce Reynolds, who played "Janie" in the 1944 film, temporarily retired to join her husband, a U.S. Marine, in Quantico, VA, according to a Feb 1945 studio press release. A 2 Feb 1945 Hollywood Reporter news item noted that director David Butler was replaced by Vincent Sherman after he was assigned to the Warner Bros. film The Time, the Place and the Girl (1946).
The role of Sgt. Spud Lee marked only the second time Dorothy Malone had won screen billing, although she had started in films at RKO in 1943. Janie Gets Married (1946) was her first 1946 film at Warner's, but it was her third that year, The Big Sleep (1946), that brought her to prominence. Ironically, her scene as a book-store clerk who enjoys an afternoon tryst with Humphrey Bogart, was one of the first she shot at Warner Bros., but the film was kept from release for over a year as the studio expanded leading lady Lauren Bacall's role.
Janie Gets Married (1946) was based on characters created in the play "Janie" by Josephine Bentham and Herschel V. Williams Jr., as produced by Brock Pemberton (New York, 10 Sep 1942).
The original Janie (1944) was only Robert Hutton's third film. A perfect on-screen match for Joan Leslie, he would co-star with her three times, with each film capitalizing on his "boy-next-door" image.