One Goofy in this short is smoking a cigarette made by a brand called "Phyllis Morrison," which is a parody of Phillip Morris. Another Goofy sky-writes an ad telling to "Smoke LOOKYs," which parodies the advertising message, "Smoke LUCKYs" (as in Lucky Strike, which was the cigarette brand Walt Disney often smoked).
Like Walt Disney, Pinto Colvig had been a longtime smoker and was suffering with lung disease at the time this short was made. He was a pioneer in the effort to require warning labels on cigarette packages. Colvig died of lung cancer in 1967, almost a year after Walt died of the same thing.