Amelia and Laura are supposed to be the same age, but Catherine Keener is a full decade older than Anne Heche.
This is the only film edited by Alisa Lepselter which was directed by someone other than Woody Allen.
Holofcener explained in an interview with Indiwire that she felt there wasn't enough space for Miramax to focus on more than one female driven movie: "Unfortunately, Miramax opened the film at the same time the company was releasing "Emma." Let's just put it this way: There was not a lot of focus on "Walking and Talking." We didn't even have a premiere or a party. I was invited to the "Emma" premiere. I think that was my consolation prize."
Nicole Holofcener saw Catherine Keener in Johnny Suede and liked her work and her look. Their first meeting was at a gym in NYC. She subsequently cast Keener in Walking and Talking (1996), Lovely and Amazing (2001), Friends with Money (2006), Please Give (2010) and Enough Said (2013).
Anne Heche was one of the many considered for the opening scene victim in Scream 3, which if she had been cast she would have been playing the girlfriend of Liev Schreiber's character, her co-star in this movie.