George A. Romero was so impressed with Simon Pegg and Edgar Wright's Shaun of the Dead (2004), that he asked them to appear in this, the fourth part of his "Dead" series, and they appear as the photo-booth zombies in the carnival and barroom sequence. They also feature prominently in the artwork for the Unrated Director's Cut.
At the beginning of the movie, if you listen carefully to the tuba and tambourine zombies in the town bandstand, they are playing notes from "The Gonk", the mall music from George A. Romero's Dawn of the Dead (1978).
This movie's Pittsburgh premiere was at the Byham Theatre, which used to be called the Fulton Theatre. This theater, when it was still the Fulton, was the same theater where Night of the Living Dead (1968) premiered in 1968.
The zombie of Tom Savini's biker character, who was killed in Dawn of the Dead (1978), can be seen in one of the scenes.
Boyd Banks: Boyd Banks, the actor who played Tucker in Dawn of the Dead (2004) and "White Man" in George A. Romero's Diary of the Dead (2007), plays "the butcher" in this movie.
George A. Romero: His voice can be heard as one of the puppets in the children's show, saying, "Take that, you smelly zombie!"