After having left the reason Michael (Jason Bateman)'s wife, Tracy (Maria Thayer), died a mystery for 2 seasons, it is strongly implied she succumbed to ovarian cancer.
In the G.V.H. Video, Gob (Will Arnett) makes reference to Happy Days (1974) star Donny Host, which the Narrator (Ron Howard), quickly corrects to Donny Most. Don Most and Howard starred together in Happy Days.
When Buster (Tony Hale) picks up the turtle, its left hand falls off (the same hand that Buster lost in episode 2.11, Out on a Limb (2005)).
There are several references to Prison Break (2005) in this episode, including a scene where Gob (Will Arnett) draws a scaffold of the prison on his body, which is a reference to Michael Scofield (Wentworth Miller)'s tattoos.