Horatio Craine is established to have been a member of the Miami Bomb Squad. The skills he learned there, would come up in many episodes throughout the shows run.
Conor O'Farrell, the actor playing Charlie Berenger, later played Undersheriff Jeffrey McKeen in season six of the original CSI.
Candy Ann Brown (Felicia Humphreys) appeared alongside David Caruso (Horatio Caine) in NYPD Blue.