- A prank in a high school science class goes terribly awry, injuring a teacher and several students. Hathaway discovers Meg's drug addiction. Weaver and Greene notice Lawrence gets easily confused.
- Carter patiently works out that high school student Howie McMurtry, brought in injured with classmates, was the remorseful one whose prank gone wrong caused a chemistry experiment explosion, probably fatal for their teacher, and leaving initiator Nathan Perez possibly blinded, compromising his athletic scholarship, infuriating his proud father enough to attack Howie, knock down Carter who intervenes and have his throat injured as Mark saves his junior. Lucy treats arts student Jesse Keenan, who swallowed paint, for that and convinces him to go in rehab having discovered cocaine in his blood, but he bails out when shifted to outdoors clinic in favor a Hathaway's pregnant junkie. When young patient Benjamin Hearn needs blood, his father insists to donate it with big brother Aaron, whom Benson finds HIV-positive and convinces to come clean, but the bigot father kicks the 'faggot' out 'no longer my son'. Kerry blindly defends to Mark her former professor Gabe, whose forgetfulness becomes obvious during the school patients flood but remains ignored.—KGF Vissers
- A high school science experiment/prank gone-wrong causes an explosion in a high-school science class floods the emergency room with patients. Lawrence's memory continues to deteriorate. Being consulted in more than 5 cases at once he losses his temper and more staff members become suspicious of his memory loss. On being confronted with Kerry he tells her that he has not faced multiple trauma cases in a long time. Elaine tells Carter that she intends to go to Europe for a couple of months. Carol finds out that the pregnant woman she is helping to quit smoking is also addicted to drugs. She convinces her to get her checked in a detox program. Lucy has a patient who is also an addict and she is trying to get her in rehab as well. Lucy and Carol compete for the one available rehab bed each of their patients needs. Dr. Dave learns about sympathy from a girl whose face was burned in the explosion. Benton inquires about DNA testing. Jeanie's home life becomes hectic, taking care of her new baby.
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