Sherman Hemsley and Isabel Sanford reprise their legendary roles as George and Louise Jefferson from The Jeffersons (1975). Hemsley also previously appeared on "Fresh Prince" in season 3 episodes 6 & 7 as 'Judge Robertson,' Phillip's opponent in the election for superior court judge.
The episode title "Will is From Mars" is a homage to the book 'Men are from Mars, Women are from Venus'.
When Will starts listing his future children's names he says one of them would be named "Willard". Will Smith's real name is Willard. But the character Will Smith is named "William Smith"