Guest stars Pat Hingle and Nan Martin, who played Mike and Paula Decker, had just a year earlier played husband and wife Horace and Laura Ford on The Incredible World of Horace Ford (1963).
The One-Armed Man has two scenes and is the center point of plot, yet the actor who plays him isn't credited. This is because at that time people who didn't speak any lines were not credited. Studios did this because credited actors received residuals from re-runs and uncredited actors did not.
Here Pat Hingle plays a role of beneficence, i.e. someone trying to help Kimble. In the only other time he appears in the series, Nicest Fella You'd Ever Want to Meet (1965), his character takes on an opposite set of morals: a sadistic cynicism bent on committing murder.
This is the second of eleven episodes in which Bill Raisch makes an appearance in the series, each time playing the one-armed man Dr. Kimble is pursuing.
This is the first of three appearances Ray Kellogg makes in the series, one other time also as a character in law enforcement: Concrete Evidence (1967). His only other appearance is as a truck driver in Never Stop Running (1964).