Although this is the only appearance John McGiver makes in this series, in the '65-'66 TV season he was kept quite busy guest starring in at least 7 different TV programs, counting this one, as well as holding down supporting roles in two movies: Made in Paris (1966) and The Glass Bottom Boat (1966).
The title is from a song made famous by Perry Como, "Make it one for ma baby an' one more for the road." Bette Midler sang the same song to Johnny Carson on his next to last Tonight Show.