This episode appears to be loosely based on two separate cases of E. coli outbreaks including
- The 1993 Jack in the Box E. coli outbreak.
- The 1996 Odwalla E. coli outbreak.
Stephen Bogardus has played three different roles over the course of the series:
- Episode 9.16 Harm (1999) - Dr. Peter Michaels.
- Episode 12.19 Slaughter (2002) - Jim Dittmar.
- Episode 20.8 Doped (2009) - Austin.