In the original script Mike Barnes, a bisexual man deliberately spreading HIV to both men and women, was murdered by one of the women he infected. AIDS activists, concerned this would lead to vigilante violence against people with AIDS, lobbied for script changes and led demonstrations that caused filming to be shut down twice.
Up here in Canada, there was a native Africaner who was HIV positive going around attacking women sexually and leaving them infected with a strain of the AIDS virus. He was found out when analysis of his victims' blood revealed that their strain of the virus was not the one endemic to Canada, leading the police right to him, a first in Canadian legal practice. He was arrested but died in prison before his trial could take place. His crime plan could have been inspired by this episode.