When Maddie, David and "Kooky" are tossing around the sample body parts, one of the parts that is thrown is labeled as "Mark Harmon". Harmon played Maddie's love interest and was thought for a time to be the father of Maddie's child.
Dr. Brill's office is located in 2121 Avenue of the Stars in Century City. Otherwise known as Nakatomi Plaza in Die Hard.