This episode takes place in 2001 and 2015.
The character Quisling shares his surname with Vidkun Quisling, a Norwegian military officer who collaborated with the Nazis during the German occupation of Norway in World War II.
Colonel Beckett shares a last name with Dr. Sam Beckett of Quantum Leap (1989) - a time traveler sent to put right what once went wrong.
According to information on a computer early in the episode, the world plague death count was 3,033,116,799. Territorial regions listed at the bottom were Asiatic, African, South American, North American, European, and Sealand.
Amy Barrett was born on June 16, 1981. In the original timeline, she died on June 10, 2009.