Grady mentions that if Fred's Pluto Water is gone, then he is too. Pluto Water was a trademarked name for a very popular strong water-based laxative product that used lithium salts as its main ingredient to help with digestion. The product was discontinued in 1971 when lithium became labeled as a controlled substance. However, the product was so popular many die-hard users stocked up on it prior to this.
The late great character actor Harry Caesar has a non-speaking uncredited funny bit as the homeless man next to Fred Sanford's bed at the Mercy Mission for the homeless.
When Fred says "Fuentes, Fuentes, Chico and Dummo," he is making a play on the names of 'the Marx Brothers': Groucho, Harpo, Chico and Gummo.
Pata de Puerco Puerto Rican is Spanish for Puerto Rican Pig's Feet.