Louie is delighted at the chance to make fun of Bobby for never getting anywhere with his acting auditions. In reality and quite ironically, Danny DeVito famously struggled as a starving artist for many years, getting turned down time and again for most acting jobs he auditioned for, before his big break with Taxi.
The title is based on a line from William Shakespeare's play 'Romeo and Juliet': O Romeo, Romeo! wherefore art thou Romeo? Deny thy father and refuse thy name.