Kansas City bootlegger Rafael Torrez (Michael Ansara) runs a lucrative trade in "Jamaica Ginger", a deadly denatured "patent medicine" sold to evade prohibition restrictions on alcohol. When rival mobsters try to move in on his operation, Torrez hires hitmen Martinson and Garrity (Brian Keith and James Coburn) to eliminate them. The hit is successful, but complications ensue when Martinson is identified to Ness. Garrity kills Martinson's girl when she refuses to provide an alibi, and then attempts to recruit Martinson for a hit on Torrez. Tipped off by Ness about his girl's murder, Martinson pretends to go along with Garrity, but instead helps Torrez to kill him. Ness and his Untouchables arrive in a blaze of gunfire and the bootleggers and hitmen are wiped out to the last man.