The series finale of "What's New, Scooby-Doo?"
E-Scream may be a pun on the gaming conference called E3.
This episode was included in Cartoon Network's Scooby-Doo! Back to School Marathon (August 10-11, 2013).
This series finale was meant to air but Kids' WB! cancelled it and burned off the schedule following the The CW merger with UPN. It was later aired on July 21, 2006 on Cartoon Network.
The trap the gang sets for the Osomons is a modified version of the trap they set for the ghost in A Clue for Scooby Doo (1969).