Professor Frink (himself an impression of Jerry Lewis dressed in the same clothes as this film's nutty professor) drinks some of the tonic and becomes a cool, sexy guy whos almost identical to Buddy Love, the nutty professor's alter ego when he drinks his tonic in this movie.
Abe and Homer are being chased and Homer remarks, "They didn't start chasing us until you turned on that getaway music." When "Foggy Mountain Breakdown" stops playing, the chase ends.