The scene where Drake and Josh realize they are stuck in the treehouse has been parodied with several memes on YouTube featuring Drake and Josh stuck in various locations.
This is the first episode where Megan gets disciplined by Audrey and Walter, although it was for helping the boys build the rocket that destroyed the treehouse. It's presumptuous to assume she doesn't get disciplined for leaving them trapped in the treehouse, since the episode ends before the parents return home.
Drake and Josh spend the majority of this episode in one location for once, like in The Wedding.
Deleted Scene (in the ending credits): Drake and Josh lie in the overturned treehouse naming adjectives to describe their predicament.
This is the first Dan Schneider show to have a reference to My Three Sons. It will be referenced in Victorious and iCarly.