When Callie is talking to Finn trying to explain Meredith's behavior, she says, "It's the doctor thing. Four years of high school, four years of college, four years of med school - by the time we graduate we are in our late 20's and we've never done anything but go to school and think about science." Finn would have spent the same amount of time in school in order to become a veterinarian.
First time someone calls Meredith 'dark and twisty'
Sara Ramirez is now billed as starring.
The beanie that Alex is wearing at the beginning of the episode is the same one that a patient (Bex) wore in season two.
The outfit Izzie is wearing in the flashback to the intern mixer is the same one she wore on her big date with Alex.