In every scene she is in, Amy Poehler sports a different hairstyle and never repeats the same one twice.
Angie has a drawer full of TASTYKAKE cupkakes. TASTYKAKE is the Philadelphia based brand that rivals Hostess and since the movie is set in Philadelphia her snack choice is locally appropriate.
Boo Boo Busters, the Professional Childproofing Company featured in this movie, is based on the real company in California. The owner of Boo Boo Busters, Kimberlee Mitchell, shipped a box of child safety devices to the production offices to use during filming, including the now infamous toilet lock Amy Poehler's character claimed was "broken."
Amy Poehler had her residence in Los Angeles professionally childproofed by the real Boo Boo Busters.
Angie is terrified to read in the parenting book that babies can be born with a full set of teeth. While not common, 1 in 2,000 babies can be born with a full set of teeth according to the National Health Institute.