Samantha's amnesia causes to a misunderstanding which leads a certain important couple to think she's racist. So Samantha decides to make Frank her first black friend. Tony is caught kissing a man and Andrea thinks it's all over now.
Samantha runs into her billionaire-ex Winston Funk and starts to question her life. Her mother proposes a trip to Vegas. However, Samantha's amnesia covers her own past in Vegas... Andrea tries to shine the image public has of her.
A rock star, Tommy Wylder, approaches Sam in a bar. Thanks to amnesia, Sam doesn't remember him. Tommy asks her out and the girls go crazy. But what is it that Sam can't remember? And what's her dad's connection to Tommy?
Turns out Regina hasn't revealed her sister Amy's existence to the amnesiac Sam - and the revelations just start from there! Andrea becomes a Jinx to Tony. Todd finds out a way to benefit from it - and also a new side out of Frank.
Sam is late from her new first date with Todd, who then gives her one last chance. Andrea thinks Sam should go for Funk instead. And Funk just happens to need Sam to meet a senator at the exact time of Sam and Todd's date.
Turns out Todd has forgotten to mention that his roommate in London is a girl. Funk's ex-wife returns and Sam, whose affair with him broke their marriage, decides to reunite them. But then Sam discovers his old romantic e-mails.