In one of the scenes where Bobby is in a coma Jared Padalecki (Sam) was twisting Jim Beaver's (Bobby) toes.
Charcot Wilbrand syndrome does not generally mean an inability to dream, rather, it affects your ability to remember or visualize images from your dreams after awakening.
Dean's alias is Robert Plant (of Led Zeppelin) when he shows his ID and badge to the doctor's test subject.
The title of this episode is from a 1931 song of the same name, popularized by, among others, the Mamas and the Papas in 1968.It also references a 1989 movie with the 2 Corey's , Corey Haim & Corey Feldman
At approximately 15:20 Bela says "So when do we go on this little magical mystery tour?". This is a reference to The Beatles 1967 album "Magical Mystery Tour".