This is the last episode of the series.
"Johnny Makeover" is a clever nod to how Johnny Bravo was redesigned in its second season, only for it to go back to the original design at the end of the series. Don Knott's line to makeover the PowerPuff Girls came to fruition in 2016 when Cartoon Network rebooted the franchise. PowerPuff Girls were also redesigned (with fingers) for the spin-off "Powerpuff Girls Z" in 2006 as well as the 2013 special "Powerpuff Girls: Dance Pantsed."