The Blood Orchid from Anacondas: The Hunt for the Blood Orchid (2004), is the flower mentioned in this film.
The film contains many references to Anaconda 2: the plot is developed around the bloody orchid, one of the main characters is fatally bitten by a spider, the plot indirectly involves the company Wexel hall, the protagonists survive by blowing up the Anaconda and the design of the Anaconda is openly inspired by the green Anaconda.
David Hasselhoff was originally going to return.
The first Anaconda film to have returning characters.
Shot back-to-back with Anaconda: The Offspring (2008).