As in the original, the conflict between the Templars and the Assassins remains a focal plot point. The Asterbego Corporation and its primary representative, Dr. Warren Vidic, remain the primary adversary of modern day protagonist Desmond Miles. The main villain of Ezio's story is Rodrigo Borgia, better known to historians as Pope Alexander VI, as well as the father of Renaissance "femme fatale" Lucrezia Borgia.