During the cancellation of the self-destruct sequence, the hand-print scanner shows two red-outlined left hands. After the self-destruct is successfully canceled, the scanner shows two right hands.
When Mike and KITT stop the truck in the pre-credits sequence, Mike opens the car door outwards. The external shot of Mike walking away from KITT shows the car door opened upwards.
In the first few seconds, a CIA 'spy satellite' is shown, but it is actually a Russian Soyuz Capsule.