Jeffrey Dean Morgan (Denny) played ghost hunter John Winchester on the show Supernatural (2005). In this episode, Morgan plays the ghost of Denny as hallucinated by Dr. Stevens (Katherine Heigl) which has also been parodied in an episode of Supernatural.
Every episode of the show is named after a famous song. "The Ties That Bind" is a song by Bruce Springsteen
Ed Lauter and Chyler Leigh were both in Not Another Teen Movie.