In "The Right Snuff" segment, the letters "KNB" appear on a screen in the spaceship. This is a reference to the KNB EFX group who do make-up effects.
In the segment Sibling Rivalry, the family dog is named Dolores Claiborne, which is the title and main character of a 1992 Stephen King novel.
In the segment The Right Snuff, one of the monitors says "HAL", another reference to 2001: A Space Odyssey (1968).
As the episode is ending and the comic pages are flipping, one of the mail away ads is for a Monkey's Paw. A version of the tale of the Monkey's Paw was told in the season 1 episode, Night of the Paw (episode 5).
The Grantham Family ashtray is on Mrs. Porter's (Molly Ringwald) desk at the beginning of the Sibling Rivalry segment.