In "Scooby's Peep-Hole Pandemonium" Scooby, Shaggy, Daphne and Scrappy works for a journalist called Orson Kane. The name is a play on words between Orson Welles and his greatest character, Charles Foster Kane. In addition, Orson Kane have great physical resemblance with the original character seen in Citizen Kane (1941).
The 90s DOS game Beneath a Steel Sky featured a similar red-bearded and hot tempered inventor in a computer laboratory.