Director Amy Do captured over 150 hours of footage, documenting the same rabbit enthusiasts at the American Rabbit Breeder's Association National Convention over the course of five years.
Amy Do initially produced Rabbit Fever as a 20-minute documentary short for her class while studying film at the University of Southern California. It wasn't until Academy-Award nominated instructor, Charles Braverman (director of the documentary Curtain Call (2000)), approached her after class and asked if he could cut a promo version of the film to pitch to television networks that Amy felt encouraged to flesh out the subject and make it feature-length.
Out of the 47 unique breeds recognized by the American Rabbit Breeders Association, Director Amy Do liked the Dwarf Hotot breed the best, which explains why that type of domestic rabbit is featured more prominently than any other breeds throughout the film.