The piece that Jerry (Jim O'Heir) plays during the Telethon is Waltz in A-flat Major, Op. 39 No. 15 by Johannes Brahms.
During the telethon, Donna calls her brother George, who is visiting their uncle in Liberia. Retta is the niece of former Liberian president Ellen Johnson Sirleaf (who was also the first elected female head of state in Africa and president during the episode's original airing)
Andy Dwyer's band Mouse Rat plays their original song "Sex Hair" during the telethon. Andy first mentioned writing this new song in Galentine's Day (2010).
When debating on whether to propose to Ann (Rashida Jones), Mark (Paul Schneider) asks someone behind the camera what he should do. This marks one of the few instances in the entire show where a character directly acknowledges the "documentary crew" filming them.
When Leslie wakes up Ron, he says that he suffers from a disorder known as "sleep fighting." In reality this would be considered as RBD (REM Sleep Behavior Disorder) which can cause "violent thrashing, punching, and kicking" during sleep.