Cast (in credits order)
| Grey Griffin | ... | Io / Narrator / Deino / Medusa (voice) (as Grey DeLisle) | |
| Greg Ellis | ... | Perseus / Soldiers / Townspeople / Spirits (voice) | |
| Tara Strong | ... | Marmara / Tekla / Townspeople (voice) | |
| Enn Reitel | ... | Spyros / Solon / Soldier / Fisherman (voice) | |
| Troy Baker | ... | Hades / Apollo / Soldiers (voice) | |
| Fred Tatasciore | ... | King Kepheus / King Satyros / Soldiers (voice) | |
| Audrey Wasilewski | ... | Queen Cassiopeia / Enyo / Spirits (voice) | |
| Jennifer Hale | ... | Andromeda / Pemphredo (voice) | |
| André Sogliuzzo | ... | Draco / Ozal / Fisherman / Spirits (voice) | |
| Crispin Freeman | ... | Prokopion / Belo / Soldiers (voice) | |
| Steve Blum | ... | Eusebios / Calibos / Guard (voice) | |
| Jim Ward | ... | Phaedrus / Kucuk / Soldiers (voice) | |
| Robin Atkin Downes | ... | Ixas / Soldiers / Townspeople (voice) | |
| Marc Graue | ... | Zeus / Fisherman / Townspeople (voice) | |
| Cam Clarke | ... | Philocrates / Fisherman / Soldiers / Spirits (voice) | |
| Steve Valentine | ... | Ikas (voice) | |
Casting By
| Collette Sunderman | ||
Production Management
| Heidi Behrendt | ... | director of production: Warner Bros. |
Art Department
| James Bede | ... | carpenter |
Sound Department
| Mark Mercado | ... | recording mixer |
Visual Effects by
| Archana Gogikar | ... | visual effects artist |
| Sirish Babu Gurrala | ... | roto supervisor: Prime Focus 3D |
| Sivaprakash Jeevanantham | ... | digital artist |
| Joseph McLamb | ... | digital matte painter: Framestore |
| Raghav Rai | ... | rotoscope artist |
Camera and Electrical Department
| Tony Roberts | ... | electrical rigger |
Transportation Department
| Aline Rajan-Harjani | ... | transportation coordinator: Canary Islands Unit |
Additional Crew
| Robert Stevenson | ... | vp online development |
| Collette Sunderman | ... | voice director |
