When Sarah and Chuck are watching TV, Chuck says there's nothing good on Monday nights. The series airs on Mondays.
While watching Spies Like Us (1985) Chuck says that you could learn a thing or two from them as a joke and Sarah disagrees. Chuck then says that he wasn't actually implying that you could learn anything from Chevy Chase and Dan Aykroyd about being a spy. Chase played the main antagonist in season 2 as the leader of Fulcrum, an espionage agency.
Christopher Lloyd's character name of "Leo Dreyfuss" is most likely a reference to the film What About Bob? (1991), where Richard Dreyfuss played psychiatrist Dr. Leo Marvin.
Casey commiserates with Ellie over Devon's malaria and says what he needs is not pills but some African snake herbs. This is done as a light bit of humor. However, this was filmed just a decade after Artemisinin became the drug of choice for treating malaria. Artemisinin is derived from sweet wormwood, which had been a folk treatment for malaria in China for over 2000 years. Western science had not even looked at this plant until the 1970s and within 30 years it had been recognized as the best available treatment.
In various episodes, when the TV sets of the Electronic's department are shown, they reveal an image or scene relating to the current episode. In this episode, at 29 minutes, they reveal Rorschach Ink Blots, which are usually used by psychiatrists.