When the press asks for her response to the death of Bobby Newport's dad, she replies, "Bummer." This is a reference to the response that Paul McCartney gave the press when asked for his reaction to the death of John Lennon.
The mansion used for the Nick Newport residence is the same mansion portrayed as the Clampett home in The Beverly Hillbillies (1962).
At 10:57, Chris Traeger (Rob Lowe) can be seen passing Leslie's bus on a road bike