The Central Coast Pharmaceuticals office is the same set used for Phillip Zurn's office in season 6's "Shawn Interrupted".
The retrieval of the hard drive image as a slow process parallels the reconstruction of the Polaroid photo in No Way Out. In fact the entire story parallels No Way Out and The Big Clock where an innocent person has to prove his innocence before time runs out.
The name of character Mitch Murray was taken from unseen characters Mitch and Murray in the David Mamet film Glengarry Glen Ross. This is also referenced by the D.R.O.S. speech as well as the 'brass balls' comment. There was also a nod to Glengarry Glen Ross when Shawn jumped on the desk and said "first prize is a Cadillac Eldorado and the second prize is a set of steak knives", which was stated by Alec Baldwin's character.
Contrary to belief Shawn is not wearing Laura's locket and has donned the same necklace all season.
This episode has multiple references to San Antonio, including the NBA team, the San Antonio Spurs. James Roday Rodriguez grew up in San Antonio.