For the role of Sam, many names have passed the casting list. Originally the production had Stan Van Samang in mind, but after some casting suggestions, Dries De Sutter's profile was a perfect fit.
The script was written years before the film was made. After a script review in December 2011, initial pre-production started late September 2012.
All scenes in the improvised laboratory were shot in an abandoned factory. The factory was planned to be demolished the day after the final shoot, putting extra pressure on the already tight schedule.