This episode was a very strong episode for Misha Collins' improvisation. There's a scene in which Collins, playing Lucifer, sits on an angels lap when talking about God's love for mankind. This moment was improvised and some of the extras can be seen laughing in the background. Another moment which wasn't in the script was the phrase Collins said, which has now became an iconic Lucifer line, "He who hesitates, disintegrates."
The show was able to circumvent the trademark infringement with the Hell's Angels motorcycle club by changing the name of the episode to "Hell's Angel" instead of "Hell's Angels".
Andrew Wheeler, who plays Noel, also played the groundskeeper possessed by Alastair in S04E15 "Death Takes a Holiday"
The preacher you hear about halfway through is from the Firesign Theatre comedy album, "Don't Crush That Dwarf, Hand Me the Pliers" released in the early 70's. This was a satire of TV and radio preachers.