Marion Cotillard voiced Charlotte Salomon in the French version of the film. She also served as executive producer of the film.
This film is Keira Knightley's first voiceover for an animated film. She was also an executive producer of the film.
Feeling the movie had limited commercial value, Canadian distributor Elevation Pictures barely promoted the movie and only gave it a limited released to select theaters. It never had a wide release.
Director and actor Xavier Dolan is one of this film's executive producers. Dolan had previously worked with Marion Cotillard in It's Only the End of the World (2016).