"Chase School" marks the first and only appearance of cat and mouse students whom are based upon the likeness of the cat-and-mouse duo.
Out of all the attire worn by the cats and mice whose teams are led by Tom and Jerry respectively, the cat and mouse students both wear bowties like Jerry while Tom is the only one without it, Tom is the only one to wear pants and shoes, Tom and the cat students' tops are orange blazers with white V-neck shirts underneath, the mouse students wear blue sweaters while Jerry wears a blazer of the same color instead and is the only mouse to wear a V-neck shirt underneath. The female cats and mice wear dresses that match their own teams' signature colors.
The episode title and character Cleocatra is a play on historical figure Cleopatra whom lived from 69 - 30 BC in Egypt.
In "Chase School", the cat students' voices are low-pitched while the mouse students' voices on the other hand are high-pitched.