Osmosis Jones (2001)
9/10
Great idea, well presented.
5 January 2005
This was a very clever idea, that effectively shows a live-action sequence, then presents the interior of a character's (Frank - Bill Murray) body in animation. The voice characters play cells and viruses withing Frank's body. I thought it was an excellent idea, very educational and entertaining at the same time. It reminded me of the classic Disney educational animated specials like "Donald Duck in Mathamagic Land" and "Goofy on Defensive Driving", and the Ludvik von Drake shorts about the atom and such stuff.

The voice casting was uniformly excellent, with a great range and personality. There were several great sight gags and action sequences in the animated sections, as well as some brilliant film spoofs (I particularly loved the TITANIC spoof and the JAWS - or general monster movie - spoof especially).

The live-action is somewhat overshadowed by the animation, but Bill Murray does play an eccentric everyman character very well - very reminiscent of his early role in CADDYSHACK, where I first noticed him. The whole zoo setting seem a little off-beat, it made me think of FIERCE CREATURES, though not as much fun. The daughter was okay, if a bit bland. And there's a great comic bit featuring actor Will Dunn as a science student which sets off a great gross-out gag.

I agree with the comments this is primarily seen as a kids movie, even though it does contain a near-death scene. But this movie definitely fits my definition of a great story idea, that is very well presented - which is the reason it made my top 100.
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