Gert-Jan and Pien are doing a pregnancy test. Mien has bought an expensive purple wig to wear during a dance night. Then Koos has an accident involving a bucket of varnish on his head.
Dr. Lydie offers unemployed children's doctor Thea a job in her practice. Koos buys an old van from Jopie. A man arrives to demonstrate a new revolutionary knife, but Lydie has forgotten to arrange an audience for him.
Mien is decorating the waiting room for Thea's new children's appointments. But Lydie seems to be busier then ever caring for little children while Thea only gets two patients on her first day.
Mien is on a diet that consists of only eating brown bread. Hans has stopped smoking with a little help from acupuncture. Lydie's even more absent minded mother is suffering from fleas.
Hans is practicing for an ice skating marathon with Thea. Both Koos and Gert-Jan express concerns that Hans may be cheating on Lydie. Mien and Koos are going to a costumed ball.
Mien goes shopping with her Turkish friend Hülya. Hans's sister Çanci is coming to stay and Lydie, Gert Jan & Koos all offer to provide her a place to stay. But Pien becomes jealous and Mien also objects.
Hans is going away for a week and Gert Jan & Pien are sleeping in Leiden. Lydie has a hangover from the going away dinner and has lost her keys. Koos and Mien are nervous about burglaries and insist on a new lock and keys.
Lydie gets a visit from her old flame Karel the dentist. Koos has bought an expensive new TV set from Jopie. Mien invites the doctor and family to come over and watch Dr. Lansberg skating in Finland.
Pregnant Pien is feeling bored and wants to teach Aerobics classes, but overprotective Gert Jan forbids it. When Gert Jan tells Pien to ask his mother for advice, Lydie wisely insists she goes for a second opinion.
A man claiming to be Lydie's father appears on her doorstep, even though she thinks the man's been dead for 40 years. Koos and Mien try out their new camper which doesn't prove itself waterproof.
Mien has started selling second hand clothes with a Turkish girlfriend, Hulya. Lydie gives them permission to clean out her attic. Koos is more reluctant when Mien and Hulya want to go out to a disco.
While discussing a name for Gert Jan & Pien's unborn child, Lydie suggests they name it after her. Meanwhile Koos & Mien are suffering from a new neighbour who is loudly renovating his house day and night.
Mien objects to Koos lending Jopie 25000 guilders. When Koos explains that women cannot understand the friendship between two men, Dr. Lydie suggests that Mien should make her husband jealous.
Mien's cunning plan to get rid of Jopie continues as he comes round to ask her out for a date. Thea and Map are thinking of going to the sperm bank for a baby.
Koos is suffering from a stomach ache but is ashamed to pull down his trousers in front of Dr. Lydie. When Lydie and Hans diagnose a acute appendicitis, he is taken to the hospital, where Mien gets lost.
Because Koos is being pampered during his hospital stay, he doesn't want to go home yet. When Dr. Lansberg spills the beans to Mien, she decides to make Koos jealous to get him home in no time.
Lydie and Hans are going on a weekend trip to Texel. Mien is sowing costumes for Gert-Jan and Pien who are going to a costumed ball dressed as Snow White and Doc. At the party, Pien goes into labor.